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What is the Endocannabinoid System? "Is Cancer Curable" "CBD Oil"
The endogenous cannabinoid system, named after the plant that led to its discovery, is perhaps the most important physiologic system involved in establishing and maintaining human health. Endocannabinoids and their receptors are found throughout the body: in the brain, organs, connective tissues, glands, and immune cells. In each tissue, the cannabinoid system performs different tasks, but the goal is always the same: homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment.
Cannabinoids promote homeostasis at every level of biological life, from the sub-cellular, to the organism, and perhaps to the community and beyond. Here's one example: autophagy, a process in which a cell sequesters part of its contents to be self-digested and recycled, is mediated by the cannabinoid system. While this process keeps normal cells alive, allowing them to maintain a balance between the synthesis, degradation, and subsequent recycling of cellular products, it has a deadly effect on malignant tumor cells, causing them to consume themselves in a programmed cellular suicide. The death of cancer cells, of course, promotes homeostasis and survival at the level of the entire organism.
Endocannabinoids and cannabinoids are also found at the intersection of the body's various systems, allowing communication and coordination between different cell types. At the site of an injury, for example, cannabinoids can be found decreasing the release of activators and sensitizers from the injured tissue, stabilizing the nerve cell to prevent excessive firing, and calming nearby immune cells to prevent release of pro-inflammatory substances. Three different mechanisms of action on three different cell types for a single purpose: minimize the pain and damage caused by the injury.
The endocannabinoid system, with its complex actions in our immune system, nervous system, and all of the body's organs, is literally a bridge between body and mind. By understanding this system we begin to see a mechanism that explains how states of consciousness can promote health or disease.
In addition to regulating our internal and cellular homeostasis, cannabinoids influence a person's relationship with the external environment. Socially, the administration of cannabinoids clearly alters human behavior, often promoting sharing, humor, and creativity. By mediating neurogenesis, neuronal plasticity, and learning, cannabinoids may directly influence a person's open-mindedness and ability to move beyond limiting patterns of thought and behavior from past situations. Reformatting these old patterns is an essential part of health in our quickly changing environment.
The federal government admits in newly funded research that compounds found in marijuana have an unprecedented ability to go in and kill brain tumors without any negative side effects.
And let’s be clear here: we’re not talking about prosecution for those who just ‘want to get high.’ In fact, as I’ve explained before, the true health effects of marijuana really don’t have to come with its infamous psychoactive effect Instead, we look to the non-THC (which is what gets you high) compounds within marijuana that are specifically known for their anti-cancer and antioxidant effects.
The endocannabinoid system is a group of endogenous cannabinoid receptors located in the mammalian brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. Known as "the body’s own cannabinoid system", The ECS is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory, and in mediating the psychoactive effects of cannabis.
Two primary endocannabinoid receptors have been identified: CB1, first cloned in 1990; and CB2, cloned in 1993. CB1 receptors are found predominantly in the brain and nervous system, as well as in peripheral organs and tissues, and are the main molecular target of the endocannabinoid ligand (binding molecule), Anandamide, as well as its mimetic phytocannabinoid, THC. One other main endocannabinoid is 2-Arachidonoylglycerol (2-AG) which is active at boEndocannabinoids are naturally occurring compounds found within the human body. They’ve been there for 600,000 years or more, but we’ve only just noticed it! One of the remarkable things about endocannabinoids is their striking similarity to the active ingredients of cannabis called phyto-cannabinoids. In fact, it was the effort by scientists to understand the exact mechanism by which cannabis works in the body that led to the discovery of the Endocannabinoid System little more than a decade ago.The science of endocannabinoid medicine has progressed to a dizzying degree in the past few years. There is wider awareness that the ‘endocannabinoid system’ is the largest neurotransmitter system in the human body, regulating relaxation, eating, sleeping, memory, and, as noted by the Italian scientist Vincenzo Di Marzo, even our immune system.
Cannabinoids promote homeostasis, the maintenance of a stable internal environment despite external fluctuations, at every level of biological life, from the sub-cellular, to the organism. For example, endocannabinoids are now understood as the source of the runner’s high. The endocannabinoids naturally found in human breast milk, which are vital for proper human development, have virtually identical effects as cannabinoids found in the cannabis plant. Amazingly, the mechanism at work after smoking or eating cannabis, when adults get the “munchies, is essentially the same as what causes breastfeeding babies to seek protein-rich milk.
Universally accepted following its discovery in 1995, the endocannabinoid system asserts it power to heal and balance the other systems of the body by turning on or off the expression of genes. Cannabinoids hold the key that unlocks receptor sites throughout the brain and immune system triggering potent healing and pain-killing effects.
Don Abrams M.D. at UCSF says the studies point to “a remarkable ability of CBD Oil to arrest cancer cell division, cell migration, metastasis, and invasiveness.” The vast impact of the endocannabinoid system on human health explains and validates anecdotal reports of cannabis used effectively for a wide range of health conditions. Studies on the efficacy of CBD Oil treatment are already driving the design and development of precision targeted single-molecule medicines. Indeed, we are hard-wired for cannabinoids.
The US government may not admit the medical efficacy of cannabis, but the global pharmaceutical industry has been researching it for many years. Some 350 scientists from drug-company labs including Merck, Pfizer, Eli Lilly, Bristol-Myers Squibb, AstraZeneca, and Allergan (maker of Botox and silicone breast implants) regularly attend meetings of the International Cannabinoid Research Society. They are all trying to develop synthetic drugs that confer some of the health benefits of cannabis without the psychoactivity. “It’s a foregone conclusion,” says Julie London, M.D.,”that the next decade will see a new generation of Big Pharma medications based on cannabis.”
According to Martin A. Lee, author of Smoke Signals, vitamin D combined with CBD Oil could become “the killer public health app of the post-prohibition era.” A new CBD/THC Oil medicine for cancer pain called Sativex from the British company, GW Pharmaceuticals, is finishing the final FDA-approval process. While there is no time limit on enduring prejudice, as science reveals more about how the cannabinoid system works, the stigma associated with cannabis use is expected to fade.
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There are a number of diseases for which CBD Oil is being administered because of its medicinal properties: THC Compounds treat cancer conditions.
Post-traumatic stress disorder (PTSD)
Other neurological disorders
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Medical Cannabis experts agree there is evidence to support the findings, cannabis "THC" whole plant tinctures on malignant cells comes from real patients who have successfully over come cancer by using cbd oil. Some have managed to completely cure their skin cancer applying cannabis oil to the affected areas, not all cannabis strains work not all whole plant cannabis oil is equal. Science of cannabis research suggest both plants high CBD and high Thc have many alternative medical benefits. Many researchers say cannabis can treat seizures, ptsd, some cancers and chronic pain patients. Whole plant endocannabinoid oil/flower appears to repair and boost quickly the bodies auto immune system. Click on "Must See To Believe" THC and CBD Oil reduced cancer tumors. Breast tumors reduced. Tumor Cells die. Learn about plant selenocompounds and Molecule Compounds in Cannabis.
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